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1.       Yanbo Wei, Shumu Li, Jingxia Wang, Chunying Shu, Jian’an Liu, Shaoxiang Xiong, Jianwen Song, Junjie Zhang, Zhenwen Zhao*, Polystyrene spheres-assisted MALDI MS for quantitative analysis of plasma lysophosphatidylcholines. Anal Chem. 2013, 85: 4729-4734.

 

2.       Hailan Liu, Xi Wu, Zizheng Dong, Zhiyong Luo, Zhenwen Zhao, Yan Xu and Jian-Ting Zhang, Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production. J Lipid Res. 2013, in press.

 

3.       Song Li, Bin Guo, Jianwen Song, Xiaoli Deng, Yusheng Cong, Pengfei Li, Ke Zhao, Lihong Liu, Gang Xiao, Feng Xu, Yingjiang Ye, Zhenwen Zhao, Menggang Yu, Yan Xu, Jianli Sang, Junjie Zhang. Plasma choline-containing phospholipids: potential biomarkers for colorectal cancer progression. Metabolomics. 2013, 9: 202–212

 

4.       Nicholas J. Skill, Wu Jianmin, Xu Yan, Zhenweng Zhao, Alfred J. Tector, Mary A. Maluccio, Lysophospholipid variants in hepatocellular carcinoma. J Surg Res. 2012 in press.

 

5.       (*联合第一作者) Qingchun Cai *, Zhenwen Zhao *, Caryl Antalis *, Libo Yan, Ali Hassan Hamed, Frederick B. Stehman, Jeanne M. Schilder, Giuseppe Del Priore, Yan Xu. Elevated and secreted PLA2 activities as new potential therapeutic targets in human epithelial ovarian cancer. FASEB J, 2012, 26: 3306-20.

 

6.       Ioanna Nikitopoulou, Nikos Oikonomou, Emmanuel Karouzakis, Ioanna Sevastou, Nefeli Nikolaidou-Katsaridou, Zhenwen Zhao, Vassilis Mersinias, Maria Armaka, Yan Xu, Masayuki Masu, Gordon B. Mills, Steffen Gay, George Kollias, and Vassilis Aidinis. Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis. J Exp Med. 2012; 209: 925-33.

 

7.       Suthat Liangpunsakul, Yasmeen Rahmini, Ruth A. Ross, Zhenwen Zhao, Yan Xu, and David W. Crabb. Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice. Am J Physiol Gastrointest Liver Physiol. 2012; 302: G515-23.

 

8.       Manuela Funke, Zhenwen Zhao, Yan Xu, Jerold Chun, and Andrew M. Tager. The Lysophosphatidic Acid Receptor LPA1 Promotes Epithelial Cell Apoptosis after Lung Injury. Am J Respir Cell Mol Biol. 2012; 46: 355-64.

 

9.       (*联合第一作者) Hui Li*, Zhenwen Zhao*, Caryl Antalis*, Zhanzhong Zhao, Robert Emerson, Gang Wei, Sheng Zhang, Zhong-Yin Zhang, Yan Xu. Combination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer development. Am J Pathol. 2011; 179: 452-61.

 

10.   Jussi Pihlajamäki, Carles Lerin, Paula Itkonen, Tanner Boes, Thomas Floss, Joshua Schroeder, Farrell Dearie, Sarah Crunkhorn, Furkan Burak, Josep C. Jimenez-Chillaron, Tiina Kuulasmaa, Pekka Miettinen, Peter J. Park, Imad Nasser, Zhenwen Zhao, Zhaiyi Zhang, Yan Xu, Wolfgang Wurst, Hongmei Ren, Andrew J. Morris, Stefan Stamm, Allison B. Goldfine, Markku Laakso, Mary Elizabeth Patti., Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metab. 2011; 14: 208-18.

 

11.   Zhenwen Zhao, Menggang Yu, Yan Xu, David Crabb, Suthat Liangpunsakul, Ethanol-induced alterations in fatty acid-related lipids in serum and tissues in mice. Alcoholism Clinical and Experimental Research, 2011, 35: 229-234. 

 

 

12.   Zhenwen Zhao, Yan Xu, An extremely simple method for extraction of lysophospholipids and phospholipids from blood samples. J Lipid Res, 2010, 51: 652-659.  PMID: 19783525.

 

13.   Hui Li, Zhenwen Zhao, Gang Wei, Libo Yan, Dongmei Wang, Hong Zhang, George Earl Sandusky, John Turk and Yan Xu, Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development. FASEB J. 2010; 24(10):4103-16.

 

14.   Jian-Min Wu, Yan Xu, Nicholas J Skill, Hongmiao Sheng, Zhenwen Zhao, Menggang Yu, Romil Saxena, and Mary A Maluccio. Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma. Mol Cancer. 2010; 9:71.

 

15.   Stella Fotopoulou, Nikos Oikonomou, Elena Grigorieva, Ioanna Nikitopoulou, Triantafillos Paparountas, Artemis Thanassopoulou, Zhenwen Zhao, Yan Xu, Dimitris L. Kontoyiannis, Eumorphia Remboutsika, Vassilis Aidinis. ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol. 2010; 339(2):451-64.

 

16.   Suthat Liangpunsakul, Margaret S. Sozio, Eric Shin, Zhenwen Zhao, Yan Xu, Ruth A. Ross, Yan Zeng, and David W. Crabb. Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels. Am J Physiol Gastrointest Liver Physiol. 2010; 298(6):G1004-12.

 

17.   Sung-Jo Kim, Zhongjian Zhang, Arjun Saha, Chinmoy Sarkar, Zhenwen Zhao, Yan Xu, Anil B. Mukherjee. Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1. Neurosci Lett. 2010; 479: 292-6.

 

18.   Zhenwen Zhao, Yan Xu, Accurate measurement of lysophosphatidic acid by ESI-MS/MS in plasma samples requires pre-separation of lysophosphatidylcholine. J Chrom B, 2009, 877: 3739-3742.

 

 

19.   Hui Li, Dongmei Wang, Hong Zhang, Kashif Kirmani, Zhenwen Zhao, Rosemary Steimetz, and Yan Xu, Lysophosphatidic acid stimulates cell migration, invasion, and colony formation as well as tumorigenesis/metastasis of mouse ovarian cancer in immunocompetent mice. Mol. Cancer Ther. 2009, 8: 1692-1701.

 

 

20.   Hui Li , Dongmei Wang , Lisam Shanjukumar Singh , Michael Berk , Haiyan Tan , Zhenwen Zhao, Rosemary Steinmetz , Kashif Kirmani , Gang Wei, Yan Xu, Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G protein-Coupled Receptor 1. Plos One, 2009; 4: e5705.

 

21.   Dongmei Wang, Zhenwen Zhao, Andrea Caperell-Grant, Gong Yang, Samuel C. Mok, Jinsong Liu, Robert M. Bigsby and Yan Xu, S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells.  Mol. Cancer Ther. 2008; 7:1993-2002.

 

22.   Andrew M Tager, Peter LaCamera, Barry S Shea, Gabriele S Campanella, Moisés Selman, Zhenwen Zhao, Vasiliy Polosukhin, John Wain, Banu A Karimi-Shah, Nancy D Kim, William K Hart, Annie Pardo, Timothy S Blackwell, Yan Xu, Jerold Chun and Andrew D Luster, The Lysophosphatidic Acid Receptor LPA1 Links Pulmonary Fibrosis to Lung Injury by Mediating fibroblast Recruitment and Vascular Leak. Nature Medicine 2008, 14, 45 – 54.

 

23.   Zhenwen Zhao, Yijin Xiao, Paul Elson, Haiyan Tan, Sarah J. Plummer, Michael Berk, Phyu Phyu Aung, Ian C. Lavery, Jean Paul Achkar, Graham Casey and Yan Xu, Plasma lysophosphatidylcholine levels: potential biomarkers for colorectal cancer. J Clin Oncology 2007, 25: 2696-2701.

 

 

24.   赵镇文,熊蕾,王振鹏,辛斌,胡伟华,熊少祥,壳聚糖的基质辅助激光解吸电离飞行时间质谱分析,析化学2007; 35: 1025-1028.

 

25.   Lisam Shanjukumar Singh, Michael Berk, Rhonda Oates, Zhenwen Zhao, Haiyan Tan, Ying Jiang, Aimin Zhou, Kashif Kirmani, Rosemary Steinmetz, Daniel Lindner, Yan Xu, Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. J. National Cancer Institute. 2007, 99: 1313-1327.

 

26.   Shu Zhang, Zhenwen Zhao, Lei Xiong, Bin Xin, Weihua Hu, Shaoxiang Xiong, A novel sample preparation method of matrix-assisted laser desorption/ionization time of flight mass spectrometry for polystyrene. Chin. Chem. Letters 2007; 18: 718-721. 

 

 

27.   王振鹏,赵镇文,辛 斌,胡伟华,熊少祥, 三苯胺偶氮化合物的MALDI—TOF质谱研究, 质谱学报,2007; 28(1): 27-31.

 

28.   刘健安,赵镇文,辛斌,胡伟华,熊少祥, 有机硼化合物的质谱分析,分析化学,2007; 35(8): 1203-1206.

 

29.   Suying Dong, Zhenwen Zhao and Huimin Ma, Characterization of Local Polarity and Hydrophobic Binding Sites of â-Lactoglobulin by Using N-Terminal Specific Fluorescence Labeling. J. Proteome Research, 2006; 5: 27-31.

 

30.   Xiaoxian Zhao, Dongmei Wang, Zhenwen Zhao, Yingyi Xiao, Saubhik Sengupta, Yijin Xiao, Renliang Zhang, Kirsten Lauber, Sebastian Wesselborg, Li Feng, Tyler M. Rose, Yue Shen, Junjie Zhang, Glenn Prestwich, and Yan Xu, Caspase-3-dependent Activation of Calcium-independent Phospholipase A2 Enhances Cell Migration in Non-apoptotic Ovarian Cancer Cells. J. Biol. Chem 2006; 281: 29357-29368.

 

31.   Juan Ren, Yi-jin Xiao, Lisam Shanjukumar Singh, Xiaoxian Zhao, Zhenwen Zhao, Li Feng, Tyler M. Rose, Glenn D. Prestwich, and Yan Xu, Lysophosphatidic Acid Is Constitutively Produced by Human Peritoneal Mesothelial Cells and Enhances Adhesion, Migration, and Invasion of Ovarian Cancer Cells. Cancer Res 2006; 66: 3006-3014.

 

32.   熊少祥, 赵镇文, 蒲丹,辛斌, 王光辉, 液相基质辅助激光解吸电离-傅里叶变换离子回旋共振质谱研究, 分析化学, 2004; 32(1): 14-18.

 

33.   Zhenwen Zhao, Shaoxiang Xiong, Xiangwen Liu, Bin Xin and Guanghui Wang. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Studies of Low Molecular Weight Dendrimers. Eur J Mass Spectrom. 2003, 9: 203-211.

 

34.   Shaoxiang Xiong, Zhenwen Zhao, Bin Xin and Guanghui Wang. Characterization of Macrocyclic Polysaccharides Using Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry. Rapid Commu. Mass Spectrom. 2003; 17: 1079-1083.

 

35.   Shaoxiang Xiong, Qinxue Ding, Zhenwen Zhao, Wenzhang Chen, Guanghui Wang and Shaojun Liu. A New Method to Improve Sensitivity and Resolution in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Proteomics 2003; 3: 265-272.

 

36.   Zhikun Wu, Qingqi Chen, Shaoxiang Xiong, Bin Xin, Zhenwen Zhao, Lijin Jiang, and Jin Shi Ma. Double-Stranded Helicates, Triangles, and Squares Formed by the Self-Assembly of Pyrrol-2- ylmethyleneamines and ZnII Ions. Angew. Chem. Int. Ed. 2003; 42: 3271-3274.

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