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134. J. Han, H.H. Liu, J.Y. Chen, K. Jia, J.M. Sun, Z. X. Nie*, Chirality-dependent Reprogramming of Macrophages, ACS Nano, 2024,18, 19597-19607.

133. J.Y. Chen, X. Yu, Y.J. Qu, X. Wang, Y.R. Wang, K. Jia, Q.Y. Du, J. Han, H.H. Liu, X.Y. Zhang, X. Z. Wang*, Z.X. Nie*, High-Performance Metabolic Profiling of High-Risk Thyroid Nodules by ZrMOF Hybrids, ACS Nano, 2024, 18, 21336-21346.

132. X. Yu, J.Y. Chen, Z.Z. Li, D. Shen, H.H. Liu*, Z. X. Nie*, Conjugate Polymer Anchor Enhancing Matrix Vacuum Stability and Improving MALDI MSI via Ion Bond, Adv. Sci., 2024, 2406296.

131. Y.R. Wang, W.B. Ma, Y.J. Qu, K. Jia, J.F. Liu, Y.Z. Li*, L.X. Jiang*, C.Q. Xiong, Z. X. Nie*, Desorption Separation Ionization Mass Spectrometry (DSI-MS) for Rapid Analysis of COVID-19, Anal. Chem., 2024, 96, 7360-7366.

130. C.Q. Xiong, Y.X. Pan, J.H. Fan, Y.Z. Li, J.Y. Wang, and Z.X. Nie*, Accurate and High-Resolution Particle Mass Measurement Using a Peak Filtering Algorithm, Anal. Chem., 2024, 96, 6511-6516.

129. R.Y. Wang, L.L. Qu, Y.R. Wang, Y.J. Qu, Q.Q. Xie, H.H. Liu*, and Z.X. Nie*, Rapid analysis and authentication of Chinese propolis using nanoelectrospray ionization mass spectrometry combined with machine learning, Food Chem., 2024, 447, 138928.

128. Y.J. Qu, M. Chen, Y.R. Wang, L.L. Qu, R.Y. Wang, H.H. Liu, L.P. Wang, and Z.X. Nie*, Rapid screening of infertility-associated gynecological conditions via ambient glow discharge mass spectrometry utilizing urine metabolic fingerprints, Talana, 2024, 274, 125969.

127. J. Han, H.H. Liu, Y.F. Li, J.Y. Chen, K. Jia, L.W. Meng, C.Q. Xiong, S.M. Chen, and Z.X. Nie*, Mass Spectrometry Imaging Reveals the Redox and Metabolic Heterogeneity, CCS Chem., 2024, 6, 1-6.

126. K. Jia, Y.W. Wang, L.X. Jiang, M. L. W.L. Liu, L.P. Wang, H.H. Liu, X.H. Cao*, Y.Z. Li*, and Z.X. Nie*, Urine Metabolic Profiling for Rapid Lung Cancer Screening: A Strategy Combining Rh-Doped SrTiO3-Assisted LDI-MS and Machine Learning, ACS Appl. Mater. Interfaces, 2024, 16, 10, 12302-12309.

125. H.H. Liu, T. Xie, J.Y. Wang, X. Wang, J. Han, Z.H. Zhu*, L.X. Jiang*, and Z.X. Nie*, In situ analysis of metabolic changes under hypoxic-ischemic encephalopathy via MALDI mass spectrometry imaging, Talanta, 2024, 168, 125306.

124. J. Fan, W.B. Ma, Y.L. Yu, Y.Z. Li*, and Z.X. Nie*, Recent advances in entirely hand-held ionization sources for mass spectrometry, Anal. Bioanal. Chem., 2024, 416, 2057. 

   

123. J.Y. Chen, L.C. Mao, Y.M. Jiang, H.H. Liu, X. Wang, L.W. Meng, Q.Y. Du, J. Han, L.Y. He, H.Y. Huang, Y.W. Wang, C.Q. Xiong*, Y. Wei, and Z.X. Nie*, Revealing the In Situ Behavior of Aggregation-Induced Emission Nanoparticles and Their Biometabolic Effects via Mass Spectrometry Imaging, ACS Nano, 2023, 17, 4463-4473.

122. Z.Z. Li, C. Sun, K. Jia, X. Wang, J. Han, J.Y. Chen, J.Y. Wang, H.H. Liu*, and Z.X. Nie*, Biofluids Metabolic Profiling for Lung Cancer Screening via Reactive Matrix-Assisted Laser Desorption Ionization Mass Spectrometry, Anal. Chem., 2023, 95, 4612-4618.

121. Y.Z. Li, K. Jia, Y.X. Pan, J. Han, J.Y. Chen*, Y.R. Wang, X.B. Ma, C.Q. Xiong, and Z.X. Nie*, Self-Cleaning Nanoelectrospray Ionization for the Analysis of High Salinity Biofluids and Single Cells, Anal. Chem., 2023, 95, 4612-4618.

120. Q.Y. Du, X. Wang, J.Y. Chen, C.Q. Xiong, W.L. Liu, J.F. Liu, H.H. Liu*, L.X. Jiang*, and Z.X. Nie*, Urine and serum metabolic profiling combines machine learning for autoimmune diseases discrimination and classification, Chem. Comm., 2023, 59, 9852-9855.

119. Q.Y. Du, X. Wang, J.Y. Chen, Y.R. Wang, W.L. Liu, L.P. Wang, H.H. Liu, L.X. Jiang, and Z.X. Nie*, Machine learning encodes urine and serum metabolic patterns for autoimmune diseases discrimination, classification and metabolic dysregulation analysis, Analyst, 2023, 148, 4318-4330.  

118. J.H. Fan, X. Wang, Y.L. Yu, Y.Z. Li*, and Z.X. Nie*, Screening of Hepatocellular Carcinoma via Machine Learning Based on Atmosphere Pressure Glow Discharge Mass Spectrometry, Analyst, 2023, 148, 337-343.

  

117. X. Wang, Y.Z. Li, J.H. Fan, L.Y. He, J.Y. Chen, H.H. Liu*, and Z.X. Nie*, Rapid screening of genitourinary cancers by mass spectrometry of urine metabolic fingerprints profiling, Chem. Comm., 2022, 58, 9433-9436.

116. L.Y. He, X. Wang, J.Y. Chen, Y.Z. Li, L.P. Wang*, C.Q. Xiong, and Z.X. Nie*, Biofluids metabolic profiling based on PS@Fe3O4-NH2 MBs assisted LDI-MS for liver cancer screening, Anal. Chem., 2022, 94, 10367-10374.

115. Y. Z. Li, L.X. Jiang, Z.P. Wang, Y.R. Wang, X.H. Cao, L.W. Meng, J.H. Fan, C.Q. Xiong*, and Z.X. Nie, Profiling of Urine Carbonyl Metabolic Fingerprints in Bladder Cancer Based on Ambient Ionization Mass Spectrometry, Anal. Chem., 2022, 94, 9894-9902.

114. L.W. Meng, J. Han, J.Y. Chen, X. Wang, X. Huang, H.H. Liu*, and Z.X. Nie, Development of an Automatic Ultrasonic Matrix Sprayer for Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging, Anal. Chem., 2022, 94, 6457-6462.

113. C.Q. Xiong, H.H. Liu, Y.Z. Li, L.W. Meng, J.Y. Wang, and Z.X. Nie*, High speed mass measurement of single metal-organic framework nanocrystal in a Paul trap, Anal. Chem., 2022, 94, 2686-2692.

112. Z.Y. Yu, Y.Shao. L.P. Ma, C.Z.i Liu, C.Y. Gu, J.J. Liu, P. He, M.X. Li, Z.X. Nie*, Z.Q. Peng*, and Y.H. Shao*, Revealing the Sulfur Redox Paths in a Li–S Battery by an In-Situ Hyphenated Technique of Electrochemistry and Mass Spectrometry, Adv. Mater. 2022, 34, 2106618.

111. Y.M. Jiang, J. Sun. X.H. Cao*, H.H. Liu*, C.Q. Xiong, and Z.X. Nie*, Laser desorption/ionization mass spectrometry imaging-A new tool to see through nanoscale particles in biological systems, Chem. Eur. J., 2022, 28, e202103710.

110. X. Wang, Y.Z. Li, Y.M. Jiang, L.W. Meng, and Z.X. Nie*, In-Depth free fatty acids annotation of edible oil by mCPBA epoxidation and tandem mass spectrometry, Food Chem., 2022, 374, 131793.

  

109. L.C. Mao, Y.M. Jiang, H. Ouyang, Y.L. Feng, R.X. Li, X.Y. Zhang, Z.X. Nie*, and Y. Wei*, Revealing the distribution of aggregation-induced emission nanoparticles via dual-modality imaging with fluorescence and mass spectrometry, Research, 2021, ID 9784053.

108. Y.M. Jiang, J. Sun*, C.Q. Xiong*, H.H. Liu, Y.Z. Li, X. Wang, and Z.X. Nie*, Mass spectrometry imaging reveals in situ behaviors of multiple components in aerosol particles, Angew. Chem. Int. Ed., 2021, 60, 23225-23231.

107. J.Y. Chen, Y.Z. Li, Y.M. Jiang, L.C. Mao, M. Lai, L.X. Jiang*, H.H. Liu*, and Z.X. Nie*, TiO2/MXene-Assisted LDI-MS for Urine Metabolic Profiling in Urinary Disease, Adv. Funct. Mat., 2021, 31, 2106743.

106. Z.Z. Li, Y.Z. Li, L.P. Zhan, L.W. Meng, X. Huang, T. Wang, Y.F. Li*, and Z.X. Nie*, Point-of-Care Test Paper for Exhaled Breath Aldehyde Analysis via Mass Spectrometry, Anal. Chem., 2021, 93, 9158-9165.

105. Y.Z. Li, J.Y. Chen, L.W. Meng, L.Y. He, H.H. Liu, C.Q. Xiong, and Z.X. Nie* Pocket-Size "MasSpec Pointer" for Ambient Ionization Mass Spectrometry, Anal. Chem., 2021, 93, 13326-13333.

104. X. Huang, H.H. Liu, D.W. Lu, Y. Lin, J.F. Liu, Q. Liu*, Z.X. Nie* and G.B. Jiang, Mass spectrometry for multi-dimensional characterization of natural and synthetic materials at the nanoscale, Chem. Soc. Rev., 2021, 50, 5243-5280.

103. L.P. Zhan, X. Huang, J.J. Xue, H.H. Liu, C.Q. Xiong*, J.Y. Wang, and Z.X. Nie*, MALDI-TOF/TOF tandem mass spectrometry imaging reveals non-uniform distribution of disaccharide isomers in plant tissues, Food Chem., 2021, 338, 127984.

102. C.Z. Liu, Y.Z. Li, C.Q. Xiong*, Z.X. Nie*, Development of Capillary-paper Spray for Small Molecules Analysis in Complex Samples, Anal. Bioanal. Chem., 2021, 413, 1099-1106.

101. P.Q. Luo, L.P. Wang, L.X. Jiang, J. Sun, Y.F. Li, H.H. Liu, C.Q. Xiong,* and Z.X. Nie, Application of Graphdiyne in Surface-Assisted Laser Desorption Ionization Mass Spectrometry, ACS Appl. Mater. Interfaces, 2021, 13, 1914-1920.

100. C.Q. Xiong, and Z.X. Nie*, Response to Comment on “A Theoretical Method for Characterizing Nonlinear Effects in Paul Traps with Added Octopole Field”, J. Am. Soc. Mass Spectrom., 2021, 32, 1271-1271.

99. Y.Z. Li, L.W. Meng, Z.Z. Li, Y.R. Wang, X. Wang, H.H. Liu, C.Q. Xiong, and Z.X. Nie*, Hand-Powered Ionization Methods for the Mass Spectrometric Detection of Small Molecules, Int. J. Mass Spectrom., 2021, 470, 116716.

98. M. Cai, K.N. Xu, Y.Z. Li, Z.X. Nie, L. Zhang, and S.Z. Luo, Chiral Primary Amine/Ketone Cooperative Catalysis for Asymmetricα Hydroxylation with Hydrogen Peroxide, J. Am. Chem. Soc. 2021, 143, 1087-1087.

97. D.S. Wei, Y.J. Yu, Y. Huang, Y.M. Jiang, Y. Zhao, Z.X. Nie, F.Y. Wang, W. Ma, Z.Q. Yu, Y.Y. Huang, X.D. Zhang, Z.Q. Liu, X.C. Zhang, and H.H. Xiao*, A Near-Infrared-II Polymer with Tandem Fluorophores Demonstrates Superior Biodegradability for Simultaneous Drug Tracking and Treatment Efficacy Feedback, ACS Nano, 2021, 15, 5428-5438.   

 

96. Y.Z. Li, L.W. Meng, G.H. Wang, X.Y. Zhou*, Z. Ouyang, Z.X. Nie*, A Gas-Phase Reaction Accelerator Using Vortex Flows, Anal. Chem., 2020, 92, 12049-12054.

95. J. Sun, Y.M. Jiang, H.H. Liu, X. Huang, C.Q. Xiong*, and Z.X. Nie*, Ultrafast photocatalytic reaction screening by mass spectrometry, Anal. Chem., 2020, 92, 6564-6570.

94. Y.Q. Liu, A.H. Xue, L.L. Ding, Y.B. Hao, H.H. Liu, M. Cui, L.H. Liu, Z.X. Nie*, and L.P. Luo*, Direct identification and metabolomic analysis of Huanglongbing associated with Candidatus Liberibacter spp. in navel orange by MALDI-TOF-MS, Anal. Bioanal. Chem., 2020, 412, 3091-3101.

93. T. Fang, R.Z. Run, C.X. Fan, Y. Sun, X. Huang, Z.X. Nie, X. Zhao, X.P. Pu*, Effects of Thymoquinone on Small-Molecule Metabolites in a Rat Model of Cerebral Ischemia Reperfusion Injury Assessed using MALDI-MSI, Metabolites, 2020, 10, 27.

 

92. J. Han, X. Huang, H.H. Liu, C.Q. Xiong*, and Z.X. Nie*, Laser Cleavable Probe for in-Situ Multiplexed Glycan Detection by Single Cell Mass Spectrometry, Chem. Sci., 2019, 10, 10958-10962.

91. C.Q. Xiong, H.H. Liu, C.Z. Liu, J.J. Xue, L.P. Zhan, and Z.X. Nie*, Mass, size and density measurement of microparticles in a Quadrupole ion trap, Anal. Chem., 2019, 91, 13508-13513.

90. Y.M. Jiang, J. Sun, Y. Cui, L.P. Zhan, P.Q. Luo, X. Huang, X.Y. Zhang, Y.R. Jiang*, and Z.X. Nie*, Ti3C2 MXene as a dual-mode substrate provides rapid differentiation and quantitation of glycan isomers using LDI-MS, Chem. Comm., 2019, 2019, 55, 10619-10622.

89. X. Huang, J.L. Jiang, Y.M. Zhang, L.P. Zhang, C.Z. Liu, C.Q. Xiong, and Z.X. Nie*, A miniature particle mass spectrometer, Anal. Chem., 2019, 91, 9393-9397.

88. Y.F. Li, P.Q. Lou, X.H. Cao, J.N. Wang, J.Y. Wang, L.P. Zhan, and Z.X. Nie*, Enhancing Surface-Assisted Laser Desorption Ionization Mass Spectrometry Performance by Integrating Plasmonic Hot-Electron Transfer Effect through Surface Modification, Chem. Comm., 2019, 55, 5769-5772.

87. L.L. Qu, Y.M. Jiang, X.Y. Huang, M. Cui, F.J. Ning, T. Liu, Y.Y. Gao, D. Wu, Z.X. Nie*, and L.P. Lou*, High-throughput Monitoring of Multiclass Syrup Adulterants in Honey Based on the Oligosaccharide and Polysaccharide Profiles by MALDI Mass Spectrometry. J. Agric. Food Chem. 2019, 67, 11256-11261.

86. L. Zhu, J. Han, Z.H. Wang*, L.H. Yin, W. Zhang, Y. Peng, and Z.X. Nie*, Competitive Adsorption on Gold Nanoparticle for Human Papillomavirus 16 L1 Protein Detection by LDI-MS, Analyst, 2019. DOI: 10.1039/c9an01612k.

85. Y.M. Jiang, J. Sun, X. Huang, H.X. Shi, C.Q. Xiong, and Z.X. Nie, Direct identification of forensic body fluids by MALDI-MS, Analyst, 2019. DOI: 10.1039/C9AN01385G.

84. S.H. Yan, L.P. Zhan, C.Z. Liu, L. Fu, R. Chen*, and Z.X. Nie, Mass spectrometry imaging of small molecule in situ in Lepidium meyenii (Maca) using gold nanoparticles matrix, Microchemical J., 2019, 150, 1040190.

83. J.M. Xu, Z.L. Zhang, R.Z. Liu, Y. Sun, H.H. Liu, Z.X. Nie, X. Zhao, X.P. Pu, Function of complement factor H and imaging of small molecules by MALDIMSI in a methamphetamine behavioral sensitization model, Behavioural Brain Research, 2019, 364, 233-244.

 

82. J.J. Xue, H.H. Liu, S.M. Chen*, C.Q. Xiong*, L.P. Zhan, J. Sun, and Z.X. Nie*, Mass spectrometry imaging of the in situ drug release from nanocarriers, Science Advances, 2018, 4, eaat9039.

81. L. Zhu, L.H. Yin, J.J. Xue, Z.H. Wang*, and Z.X. Nie*, Mass Spectrometry Genotyping of Human Papillomavirus based on Nano Materials High- Efficiency Selective Enrichment, ACS Appl. Mater. Interfaces, 2018, 10, 41178-41184.

80. J.L. Liu, W. Tang, X.Z. Meng, L.P. Zhan, W. Xu*, Z.X. Nie*, and Z.L. Wang*, Improving the Performance of Mini 2000 Mass Spectrometer with A Triboelectric Nanogenerators Electrospray Ionization Source, ACS Omega, 2018, 3, 12229-12234.

79. Y.F. Li, X.H. Cao, L.P. Zhan, J.J. Xue, J.Y. Wang, C.Q. Xiong, and Z.X. Nie*, Hot Electron Transfer Promotes Ion Production in Plasmonic Metal Nanostructure Assisted Laser Desorption Ionization Mass Spectrometry, Chem. Comm. 2018, 54, 10905-10908.

78. L.P. Zhan, Y. Liu, X.B. Xie, C.Q. Xiong, and Z.X. Nie*, Heat-induced Rearrangement of Disulfide Bond of Lactoglobulin Characterized by Multiply Charged MALDI-TOF/TOF Mass Spectrometry, Anal. Chem. 2018, 90, 10670-10675.

77. J. Han, Y.F. Li, L.P. Zhan, J.J. Xue, J. Sun, C.Q. Xiong*, and Z.X. Nie*, A Novel Mass Spectrometry Method Based on Competitive Non-covalent Interaction for the Detection of Biomarkers, Chem. Comm. 2018 54, 10726-10729.

76. X. Huang, L.P. Zhan, J. Sun, J.J. Xue, H.H. Liu, C.Q. Xiong, and Z.X. Nie*, Utilizing a Mini-humidifier To Deposit Matrix For MALDI-Imaging, Anal. Chem. 2018, 90, 8309-8313.

75. J. Sun, H.H. Liu, L.P. Zhan, C.Q. Xiong, X. Huang, J.J. Xue, and Z.X. Nie*, Laser cleavable probes-based cell surface engineering for in-situ sialoglycoproteins profiling by LDI mass spectrometry, Anal. Chem. 2018, 90, 6397-6402.

74. L.P. Zhan, X.B. Xie, Y.F. Li, H.H. Liu, C.Q. Xiong, and Z.X. Nie*, Differentiation and Quantitation of Disaccharide Isomers by MALDI-TOF/TOF Mass Spectrometry, Anal. Chem. 2018, 90, 1525-1530.

73. H.H. Liu, Y.M. Zhou, J.Y. Wang, C.Q. Xiong, J.J. Xue, L.P. Zhan, and Z.X. Nie*, N-Phenyl-2-naphthylamine As a Novel MALDI Matrix for Analysis and In Situ Imaging of Small Molecules, Anal. Chem. 2018, 90, 729-736.

72. L.Z. Liu, S. Chen, Z.J. Xue, Z. Zhang, X.Z. Qiao, Z.X. Nie, D. Han, J.L. Wang and T. Wang*, Bacterial capture efficiency in fluid bloodstream improved by bendable nanowires, Nat. Commun. 2018, 9, 444.

71. Z.Y. Zhang, Z. Zhang, H.H. Liu, X. Mao, W. Liu, S.T. Zhang, Z.X. Nie, and X.Q. Lu*, Ultratrace and robust visual sensor of Cd2+ ions based on the size-dependent optical properties of Au@g-CNQDs nanoparticles in mice models, Biosensors Bioelectronics, 2018, 103, 87-93.

70. S.H. Yang, H.H. Liu, X. Huang, L.P. Zhan, P. Q. Lou, J.J. Xue, R. Chen*, and Z.X. Nie, The metabolism and distribution of imidazole alkaloids from Lepidium meyenii (Maca) in mouse by matrix-assisted laser desorption/ionization mass spectrometry imaging, Int. J. Mass Spectrom., 2018, 434, 93-99.

 

69. J.N. Wang, J. Sun, J.Y. Wang, H.H. Liu, J.J. Xue and Z.X. Nie*, Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry, Chem. Comm. 2017, 53, 8114-8117. (Back outside cover).

68. X.B. Xie, Z.P. Wang, Y.F. Li, L.P. Zhan, and Z.X. Nie*, Investigation and Applications of in-source oxidation in Liquid Sampling-Atmospheric Pressure Afterglow Microplasma ionization (LS-APAG) source, J. Am. Soc. Mass Spectrom. 2017, 28, 1036-1047.

67. H.H. Liu, W. Li, Q. He, J.J. Xue, J.Y. Wang, C.Q. Xiong, X.P. Pu, and Z.X. Nie*, Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction, Sci. Rep. 2017, 7, 41954.

66. J.J Xue, Y.F. Li, X.B. Xie, C.Q. Xiong, H.H. Liu, S.M. Chen, Z.X. Nie,* C.C. Chen, and J.C. Zhao*, Characterization of Organic Aerosol in Beijing by Laser Desorption Ionization Coupled with Fourier Transform Ion Cyclotron Resonance Mass spectrometry, Atmospheric Environment, 2017, 159, 55-65.

65. R.Z. Liu, C.X. Fan, Z.L. Zhang, X. Zhao, Y. Sun, H.H. Liu, Z.X. Nie, and X.P. Pu*, Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging, J. Mol. Sci., 2017, 18, 2451.

 

64. C.Q. Xiong, X.Y. Zhou, Q.He, X. Huang, J.Y. Wang, W.-P. Peng, H.-C. Cheng, and Z.X. Nie*, The development of visible-wavelength MALDI cell mass spectrometry (CMS) for high-efficiency single-cell analysis, Anal. Chem. 2016, 88, 11913-11918.

63. N. Zhang, K. Zhu, C.Q. Xiong, Y.R. Jiang, H.-C. Cheng, and Z.X. Nie*, Mass measurement of single intact nanoparticles in a cylindrical ion trap, Anal. Chem. 2016, 88, 5958-5962.

62. J. Hou, Q.N. Zheng, C.Q. Xiong, C.Z. Guan, S.M. Chen, N. Zhang, Y.F. Li, Q. He, X.B. Xie, J.N. Wang, Z.X. Nie*, D.Wang*, and L.J. Wan*, Ambient Electrospray Soft-landing for Printing Non-covalent Molecular Nanostructures using Charged Molecular Ink, Chem. Comm. 2016, 52, 13660. (Back inside cover).

61. N. Zhang, J. Hou, S.M. Chen, C.Q. Xiong, H.H. Liu, Y.L. Jin, J.N. Wang, Q. He, R. Zhao, and Z.X. Nie*, Rapidly Probing Antibacterial Activity of Graphene Oxide by Mass Spectrometry-based Metabolite Fingerprinting, Sci. Rep. 2016, 6, 28045.

60. Y.F. Li, J.N. Wang, L.P. Zhan, M. Wleklinski, J.Y. Wang, C.Q. Xiong, H.H. Liu, Y.M. Zhou, and Z.X. Nie*, The Bridge between thin layer chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry: The realization of liquid thin layer chromatography-mass spectrometry (LTLC-MS), J. Chrom. A. 2016, 1460, 181-189.

59. J. Sun, S.M. Chen, H.H. Liu, C.Q. Xiong, J.Y. Wang, X.B. Xie, J.J. Xue, P.L. Chen, and Z.X. Nie*, Fluorographene nanosheets:A new carbon-based matrix for the detection of small molecules by MALDI-TOF MS, RSC Adv., 6, 99714-99719.

58. C.Q. Xiong*, X.Y. Zhou, N. Zhang, L.P. Zhan, Y.T. Chen, and Z.X. Nie*, Nonlinear Ion Harmonics in the Paul Trap with Added Octopole Field: Theoretical Characterization and New Insight into Nonlinear Resonance Effect, J. Am. Soc. Mass Spectrom. 2016, 27, 344-351.

57. J. Hou, S.M. Chen, C.Y. Cao, H.H. Liu, C.Q. Xiong, J.N. Wang, N. Zhang, Q. He, W.G. Song, and Z.X. Nie*, Flowerlike MgO/Organic Salt Matrix to Assist LDI Mass Spectrometry for Analysis of Lead in Natural Samples, Rapid Commun. Mass Spectrom., 2016, 30, 208-216.

56. J. Sun, Q. He, J.J. Xue, C.Q. Xiong, H.H. Liu, S.M. Chen* and Z.X. Nie*, Review of matrix-assisted laser desorption/ionization mass spectrometry in analysis and imaging of small molecules, Scientia Sinica Chimica, 2016, 46, 1119-1125.

 

55. X. B. Xie, L. Zhang, Q. He, J. Hou, C. M. Xu, N. Zhang, S. Z. Luo*, and Z. X. Nie*, Copper-catalyzed Aerobic Autoxidation of N-Hydroxycarbamates Probed by Mass Spectrometry, Chem. Eur. J., 2015, 21, 14630-14637.

54. S.M. Chen, C.Q. Xiong, H.H. Liu, Q.Q. Wan, J. Hou, Q. He, A. Badu-Tawiah, and Z.X. Nie*, Mass Spectrometry Imaging Reveals the Sub-organ Distribution of Carbon Nanomaterials, Nature Nanotech. 2015, 10, 176-182.

53. Q. He, A.K. Badu-Tawiah*, S.M. Chen, C.Q. Xiong, H.H. Liu, YM. Zhou, J. Hou, N. Zhang, Y.F. Li, X.B. Xie, J.N. Wang, L.Q. Mao, and Z.X. Nie*, Reactive Charged-droplets for Ambient Surface Modification Studied using Cyclic Voltammetry, Anal. Chem. 2015, 87, 3144-3148.

52. J.N. Wang, S.L. Qiu, S.M. Chen, C.Q. Xiong, H.H. Liu, J.Y. Wang, N. Zhang, J. Hou, Q. He, and Z.X. Nie*, MALDI-TOF MS Imaging of Metabolites with N-(1-naphthyl) Ethylenediamine Dihydrochloride (NEDC) Matrix and its Application to Colorectal Cancer Liver Metastasis, Anal. Chem. 2015, 87, 422-430.

51. C.Q. Xiong, X.Y. Zhou, N. Zhang, L.P. Zhan, and Z.X. Nie*, A Theoretical Method for Characterizing Nonlinear Effects in Paul Traps with Added Octopole Field, J. Am. Soc. Mass Spectrom. 2015, 26, 1338-1348. (Cover paper).

 

50. Huihui Liu, Rui Chen, Jiyun Wang, Suming Chen, Caiqiao Xiong, Jianing Wang, Jian Hou, Qing He, Ning Zhang, Zongxiu Nie*, Lanqun Mao*, 1,5-diaminonaphthalene hydrochloride assisted laser desorption/ionization mass spectrometry imaging of small molecules in tissues following focal cerebral ischemia, Anal. Chem., 2014, 86, 10114-10121.

49. Caiqiao Xiong, Xiaoyu Zhou, Ning Zhang, Lingpeng Zhan, Suming Chen, Jiyun Wang, Wen-Ping Peng, Huan-Cheng Chang, Zongxiu Nie*, Quantitative assessment of protein adsorption on microparticles with particle mass spectrometry, Anal. Chem. 2014, 86, 3876-3881.

48. Yueming Zhou, Ning Zhang, Yafeng Li, Caiqiao Xiong, Suming Chen, Yongtai Chen, Zongxiu Nie*, Plasma-based ambient sampling/ionization/transmission integrated source for mass spectrometry, Analyst, 2014, 139, 5387-5392.

47. Caiqiao Xiong, Xiaoyu Zhou, Ning Zhang, Lingpeng Zhan, Suming Chen, Zongxiu Nie*, Nonlinear effects in paul traps operated in the second stability region: analytical analysis and numerical verification ,J. Am. Soc. Mass. Spectrom., 2014, 25, 1882-1889.

46. J. Hou, S.M. Chen, J.N. Wang, C.Y. Cao, Q. He, J.Y. Wang, W.G. Song and Z.X. Nie*, Identification of Metal Ions in natural samples and MgO assisted lead profiling by MALDI Mass Spectrometry, Analyst, 2014, 139, 3469-3475.

45. N. Zhang, L.P. Zhan, C.Q. Xiong*, Z.X. Nie*,Review of Particle ion trap mass spectrometry,Scientia Sinica Chimica, 2014, 44, 801-806.

44. S.J. Wang, S.M. Chen, J.N. Wang, P. Xu, Y.M. Luo, Z.X. Nie*, and W.B. Du*, Interface Solution Isoelectric Focusing with in situ MALDI-TOF Mass Spectrometry, Electrophoresis, 2014, 35, 2528-2533.

43. J.T. Hu, H.C. Xu, P.J. Nie, X.B. Xie, Z.X. Nie*, and Y. Rao*, Synthesis of indazoles and azaindazoles by aerobic oxidative C-N coupling under transition metal free conditions, Chem. Eur. J. 2014, 20, 3932-3938.

42. Y.Y. Lv, L.S. Yu*, C.M. Jiang, S.M. Chen, and Z.X. Nie*, Synthesis of Layer-number-controlled Graphene Nanosheets Powder by Soluble Salt-assisted Route, RSC Adv. 2014,4, 13350-13354.

41. Luliang Wang, Juan Qiao, Huihui Liu, Jie Hao, Li Qi*, Xiaoping Zhou, Dan Li*, Zongxiu Nie, Lanqun Mao, Ratiometric fluorescent probe based on gold nanoclusters and alizarin red-boronic acid for monitoring glucose in brain microdialysate, Anal. Chem., 2014, 86, 9758-9764.

40. Liping Li, Shuai Chen, Linnan Xu, Yu Bai*, Zongxiu Nie, Huwei Liu, Limin Qi*, Template-free synthesis of uniform mesoporous SnO2 nanospheres for efficient phosphopeptide enrichment,J. Mater. Chem. B, 2014, 2, 1121-1124.

 

39. S.M. Chen, H.Z. Zheng, J.N. Wang, J. Hou, Q. He, H.H. Liu, X.L. Kong, and Z.X. Nie*, Carbon Nanodots As a Matrix for the Analysis of Low-Molecular-Weight Molecules in both Positive and Negative Ion MALDI-TOF MS and Quantification of Glucose and Uric Acid in Real Samples, Anal. Chem. 2013, 85, 6646-6652.

38. C.Q. Xiong, X.Y. Zhou, J.N. Wang, N. Zhang, S.M. Chen, W.-P. Peng, H.-C. Chang, and Z.X. Nie*, Ambient Aerodynamic Desorption/ionization Method for Microparticle Mass Measurement, Anal. Chem. 2013, 85, 4370-4375.

37. Y.F. Li, N. Zhang, J.N. Wang, Y.M. Zhou, C.Q. Xiong, S.M. Chen, and Z.X. Nie*, Induced Dual-Nanospray: A Novel Internal Calibration Method for Accurate Mass Measurement in Real Sample, J. Am. Soc. Mass Spectrom. 2013, 24, 1446-1449.

36. X.Y. Zhou, C.Q. Xiong, S. Zhang, N. Zhang, and Z.X. Nie*, Study of nonlinear resonance effect in Paul trap, J. Am. Soc. Mass Spectrom. 2013, 24, 794-800.

35. C. Zhen, Y.M. Zhou, N. Zhang, J.Y. Wang, and Z.X. Nie*, Differentiation of Chinese Liquors by Using Ambient Glow Discharge Ionization, Analyst 2013, 138, 3830-3835.

34. Q. He, S.M. Chen, J.N. Wang, J. Hou, J.Y. Wang, S.X. Xiong, Z.X. Nie*, 1-Naphthylhydrazine Hydrochloride: A New Matrix for the Quantification of Glucose and Homogentisic Acid in Real Samples by MALDI-TOF MS, Clin. Chim. Acta 2013, 420, 94-98.

33. N. Zhang, Y.F. Li, Y.M. Zhou, J. Hou, Q. He, X.G. Hu, Y.M. Jia, C.Y. Yu, and Z.X.Nie*, Rapid detection of polyhydroxy alkaloids in mulberry using leaf spray mass spectrometry, Anal. Meth. 2013, 5, 2455-2460.

32. C.-C. Hsieh, J.Y. Gou, S.-U. Hung, R. Chen, Z.X. Nie, H.-C. Chang, and C.-C. Wu*, Quantitative Analysis of Oligosaccharides Derived from Sulfated Glycosaminoglycans byNanodiamond-Based Affinity Purification and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry, Anal. Chem. 2013, 85, 4342-4349.

31. Y.T. Yang, F.J. Huo, C.X. Yin*, A.M. Zheng, J.B. Chao, Y.Q. Li, Z.X. Nie, R. Martines-Manez, and D.S. Liu, Thiol-Chromene click chemistry: A coumarin-based derivativeand its use as regenerable thiol probe and in bioimaging applications, Biosensors and Bioelectronics 2013, 47, 300-306.

30. Li-Ping Li, Tao Zheng, Lin-Nan Xu, Ze Li, Ling-Dong Sun, Zong-Xiu Nie, Yu Bai, and Hu-Wei Liu, SnO2-ZnSn(OH)6: a novel binary affinity probe for global phosphopeptide detection, Chem. Commun.2013, 49, 1762-1764.

29. M. N. Wang , Y.X. Fan, Y.C. Han, Z.X. Nie, and Y.L. Wang*, Coacervation of cationic gemini surfactant with N-Benzoylglutamic acid in aqueous solution, Langmuir 2013, 29, 14839-14847.

28. X.Y. Mu , L. Qi* , P. Dong , J. Qiao, J. Hou, Z.X. Nie, H.M. Ma, Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron, Biosensors and Bioelectronics 2013, 49, 249-255.

 

27. S.M. Chen, L. Chen, J.N. Wang, J. Hou, Q. He, J.A. Liu, J.Y. Wang, S.X. Xiong, G.Q. Yang and Z.X. Nie* , 2,3,4,5-Tetrakis (3',4'-dihydroxylphenyl) thiophene: A New Matrix for the Selective Analysis of Low Molecular Weight Amines and Direct Determination of Creatinine in Urine by MALDI-TOF MS, Anal. Chem. 84, 10291-10297 (2012).

26. N. Zhang, Y.M Zhou, C. Zhen, Y.F. Li, C.Q. Xiong, J.Y. Wang, H.Y. Li, Z.X. Nie*, Structural characterization of synthetic polymers using Thermal-Assisted Atmospheric Pressure Glow Discharge Mass Spectrometry, Analyst , 137 , 5051-5056(2012).

25. R. Chen, S.M. Chen, C.Q. Xiong, C.-C. Wu*, X.L. Ding, S.X. Xiong, H.-C. Chang, and Z. X. Nie*, N-(1-Naphthyl) Ethylenediamine Dinitrate: A New Matrix for Negative Ion MALDI-TOF MS Analysis of Small Molecules, J. Am. Soc. Mass Spectrom, 23, 1454-1460 (2012).

24. C.Q. Xiong, X.Y. Zhou, J.N. Wang, R. Chen, Y. Tang, W.-P. Peng, H.-C. Chang, Z. X. Nie*, The development of charge detection quadrupole ion trap mass spectrometry (CD-ITMS) driven by rectangular and triangular waves, Analyst, 137, 1199-1204 (2012).

23. X.Y. Zhou, G.P. Xu, C.Q. Xiong, R. Chen, H.X. Qiao, and Z. X. Nie*, Characteristicsof electrical field in surface-electrode ion traps, J. Mass Spectrom.47, 286-293 (2012).

22. R. Chen, W.J. Xu, C.Q. Xiong, X.Y. Zhou, S.X. Xiong, Z. X. Nie*, L.Q. Mao, Y. Chen, and H.-C. Chang*, A high-salt-tolerance matrix for facile detection of glucose in rat brain microdialysates by MALDI mass spectrometry, Anal. Chem. 84, 465-469 (2012).

 

21. C.Q. Xiong, X.Y. Zhou, R. Chen, Y.M. Zhang, W.-P. Peng, Z. X. Nie*, H.-C. Chang, H.W. Liu, and Y. Chen, Characterization of column packing materials in high-performance liquid chromatography by charge-detection quadrupole ion trap mass spectrometry, Anal. Chem. 83, 5400-5406 (2011).

20. R. Chen, L.P. Wang, C.Q. Xiong, Y.M. Zhou, C. Zhen, N. Zhang, Y. Tang, X.Y. Zhou, J.N. Wang, Z. X. Nie* and Y. Chen, Direct Analysis of Oligosaccharides and Alpha Hydroxy Acids in Fruits Using Electrosonic Spray Ionization Mass Spectrometry, Analyst,136,3809,(2011).

19. Z. Q. Zhu, C. Q. Xiong, G. P. Xu, H. Liu, X. Y. Zhou, R. Chen, W. P. Peng*, and Z. X. Nie* , Characteristics of bioparticles using a miniature cylindrical ion trap mass spectrometer operated at rough vacuum, Analyst , 136 , 1305 (2011).

18. X. Y. Zhou, C. Q. Xiong, G. P. Xu, L. Hao, Y. Tang, Z. Q. Zhu, R. Chen, H. W. Qiao, Y. H. Tzeng, W. P. Peng, Z. X. Nie* , and Y. Chen* , Potential distribution and transmission characteristics in a curved quadrupole ion guide, J. Am. Soc. Mass Spectrom. 22, 386 (2011).

17. J. Lv, L. Zhang, Y. M. Zhou, Z. X. Nie, S. Z. Luo,* and J. P. Cheng, Asymmetric Binary Acid Catalysis: A Regioselectivity Switch between Enantioselective 1,2- and 1,4-Addition through Different Counteranions of InIII, Angew. Chem. Int. Ed. 50, 6601-6614 (2011).

 

16. X.Y. Zhou, Z.Q. Zhu, C.Q. Xiong, R. Chen, W.J. Xu, H.W. Qiao, W.P. Peng, Z. X. Nie*, and Y. Chen*, Characteristics of stability boundary and frequency in nonlinear ion trap mass spectrometer, J. Am. Soc. Mass Spectrom. 21, 1588 (2010).

15. F.J. Hou, J. Su, Y.Q. Sun, C.X. Yin*, H.B. Tong, Z.X. Nie, A rhodamine-based dual chemosensor for the visual detection of copper and the ratiometric fluorescent detection of vanadium, Dyes & Pigments, 2010, 86, 50-55.

 

14. L. Gao, G. T. Li, J. Cyriac, Z. X. Nie, and R. Graham Cooks, Imaging of surface charge and the mechanism of desorption electrospray ionization mass spectrometry, J. Phys. Chem. C, 114, 5331 (2010).

13. Z. X. Nie, G. T. Li, M. P. Goodwin, L. Gao, J. Cyriac, and R. Graham Cooks, In situ SIMS analysis and reactions of surfaces after soft-landing of mass-selected cations and anions in an ion trap mass spectrometer, J. Am. Soc. Mass Spectrom. 20, 949(2009).

12. L. Gao, G. T. Li, Z. X. Nie , J. Duncan, Z. Ouyang, and R. Graham Cooks, Characterization of a discontinuous atmospheric pressure interface and use of multiple ion introduction pulses method for performance improvement, Int. J. Mass Spectrom. 283, 30(2009).

11. Z. X. Nie, F. P. Cui, M.-L. Chu, C.-H. Chen, and H.-C. Chang, Calibration of frequency-scan Quadrupole ion trap mass spectrometer for microparticles mass analysis, Int. J. Mass Spectrom. 270, 8 (2008).

10. W.-P. Peng, M. P. Goodwin, Z. X. Nie, M. Volny, Z. Ouyang, and R. Graham Cooks, Ion soft landing using a rectilinear ion trap mass spectrometer, Anal. Chem. 80 , 6640 (2008).

9. Z. X. Nie, F. P. Cui, Y.-K. Tzeng, H.-C. Chang, M.-L. Chu, H.-C. Lin, C.-H. Chen, H.-H. Lin, and A.-L. Yu, High-speed mass analysis of whole erythrocytes by charge-detection Quadrupole ion trap mass spectrometry, Anal. Chem. 79 , 7401 (2007).

8. Z. X. Nie, Y.-K. Tzeng, H.-C. Chang, C.-C. Chiu, C.-Y. Chang, C.-M. Chang and M.-H. Tao Microscopy-based mass spectrometry of single whole virus in a cylindrical ion trap, Angew. Chem. Int. Ed. 45 , 8131 (2006).

7. W.-P.Peng, Y.-C.Yang, M.-W.Kang, Y.-K.Tzeng, Z. X. Nie, H.-C.Chang, W.Chang, and C.-H.Chen, Laser-induced acoustic desorption mass spectrometry of single bioparticles Angew. Chem. Int. Ed. 45 , 1423 (2006).

6. Z. X. Nie, C.-W. Lin, W.-P. Peng , Y. T. Lee, and H.-C. Chang, Frequency scan of a quadrupole mass analyzer in the third stability region for protein analysis, J. Chin. Chem. Soc. ( Taipei ) 53 , 47 (2006).

5. Z. X. Nie, J.M. Li, Y.R. Jiang, Y.W. Zhu, H. Guan, H.L. Shu, H.L. Shao, and K.L. Gao, Character of store and reaction of ground multiply charged Fen+ (n=1-3) ions in a Paul trap, 物理学报, 53 , 1034 (2004).

4. K.L. Gao* (导师), Z. X. Nie, Y.R. Jiang, and J.M. Li, Measurement of charge transfer rate of Fe3+ ion coefficients with H2, N2 at electron-volt energy, Phys. Rev. A 67 , 022702 (2003).

3. 蒋玉蓉,聂宗秀,李交美,高克林,射频阱中基态 Sc3+、Ti3+多电荷离子的产生及存储特性, 中国激光, 28 ( 2 ) 2002.

2. Z. X. Nie, M. Feng, J.M. Li, L. Shi, X.W. Zhu, and K.L. Gao, Effect of the double frequency of trap field in a Paul trap, Commu. Theor. Phys. 15, 593 (2001).

1. Y.R. Jiang, Z. X. Nie, J.M. Li, and K.L. Gao, Charge transfer of Sc3+ with N2 and H2 at electron-volt Energy, Chin. Phys. Lett. 18, 528 (2001).

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