1. Wenjing Wu, Xing Li, Lingyu Zhao, Shumu Li, Juanjuan Han, Yangyang Zhang* and Zhenwen Zhao *, Design and synthesis of a deep tissue penetrating near-infrared two-photon fluorescence probe for the specific detection of NQO1, Chem. Commun., 2022, 58, 5634-5637.
2. Yangyang Zhang, Wenjing Wu, Junjie Zhang, Zhao Li, Huimin Ma, and Zhenwen Zhao*, Facile Method for Specifically Sensing Sphingomyelinase in Cells and Human Urine Based on a Ratiometric Fluorescent Nanoliposome Probe, Anal. Chem. 2021, 93, 11775−11784.
3. Tuo Li, Hui Yang, Xing Li, Yinzhu Hou, Yao Zhao, Wenjing Wu, Lingyu Zhao, Fuyi Wang and Zhenwen Zhao*, Open-flow microperfusion combined with mass spectrometry for in vivo liver lipidomic analysis, Analyst, 2021, 146, 1915–1923.
4. Wei Ren, Fuchun Nan, Shumu Li, Sijin Yang,* Jiechao Ge,* and Zhenwen Zhao*, Red Emissive Carbon Dots Prepared from Polymers as an Efficient Nanocarrier for Coptisine Delivery in vivo and in vitro, ChemMedChem 2021, 16, 646-653.
5. Shumu Li, Jian’an Liu, Jiping Sun, Zhenpeng Wang, Kai Wang, Lei Guo, Shuliang Yang, Jinchao Wei, Xiangjun Zheng, Zhenwen Zhao,* Co-NC as adsorbent and matrix providing the ability of MALDI MS to analyze volatile compounds, Chinese Chemical Letters 32 (2021) 62-65.
6. Xing Li, Tuo Li, Zhenpeng Wang, Jinchao Wei, Jianan Liu, Yangyang Zhang, Zhenwen Zhao,* Distribution of perfluorooctane sulfonate in mice and its effect on liver lipidomic, Talanta 226 (2021) 122150.
7. Na Li, Shumu Li, Tuo Li, Hui Yang, Yangyang Zhang, and Zhenwen Zhao*, Co-Incorporated Mesoporous Carbon Material-Assisted Laser Desorption/Ionization Ion Source as an Online Interface of In Vivo Microdialysis Coupled with Mass Spectrometry, Anal. Chem. 2020, 92, 5482−5491.
8. Na Li, Peng Wang, Xiaolong Liu, Chao Han, Wei Ren, Tuo Li, Xing Li, Fengyun Tao, and Zhenwen Zhao*, Developing IR-780 as a Novel Matrix for Enhanced MALDI MS Imaging of Endogenous High-Molecular-Weight Lipids in Brain Tissues, Anal. Chem. 2019, 91, 15873−15882.
9. Chao Han, Shumu Li, Qingwei Yue, Na Li, Hui Yang and Zhenwen Zhao*, Polydopamine-capped AgNPs as a novel matrix overcoming the ion suppression of phosphatidylcholine for MALDI MS comprehensive imaging of glycerophospholipids and sphingolipids in impact-induced injured brain, Analyst, 2019, 144, 6304-6312.
10. Wei Ren, Shiqing Chen, Yuyang Liao, Shumu Li, Jiechao Ge, Fengyun Tao, Qing Huo, Yangyang Zhang,* Zhenwen Zhao,* Near-infrared fluorescent carbon dots encapsulated liposomes as multifunctional nano-carrier and tracer of the anticancer agent cinobufagin in vivo and in vitro, Colloids and Surfaces B: Biointerfaces 174 (2019) 384-392.
11. Hui Yang, Shilei Li, Qian Zhang, Zhenpeng Wang, Na Li, Chao Han, Qing Huo, Zhenwen Zhao,* Combination of electrospray deposition technology of TiO2 nanoparticles and MALDI FTICR MSI for identification of fingerprint morphology and latent components, Talanta 198 (2019) 310-315.
12. Ming Guan, Zhen Zhang, Shilei Li, Jian’an Liu, Lu Liu, Hui Yang, Yangyang Zhang, Tie Wang, Zhenwen Zhao,* Silver nanoparticles as matrix for MALDI FTICR MS profiling and imaging of diverse lipids in brain, Talanta 179 (2018) 624-631.
13. Hui Yang, Wenliang Ji, Ming Guan, Shilei Li, Yangyang Zhang, Zhenwen Zhao*, Lanqun Mao, Organic washes of tissue sections for comprehensive analysis of small molecule metabolites by MALDI MS imaging of rat brain following status epilepticus, Metabolomics (2018) 14:50.
14. Hui Yang, Tuo Li, Lu Liu, Na Li, Ming Guan, Yangyang Zhang, Zhenpeng Wang and Zhenwen Zhao*, Metal–organic frameworks as affinity agents to enhance the microdialysis sampling efficiency of fatty acids, Analyst, 2018, 143, 2157.
15. Wei Ren, Shiqing Chen, Shumu Li, Yangyang Zhang, Jianan Liu, Ming Guan, Hui Yang, Na Li, Chao Han, Tuo Li, Zhenwen Zhao,* and Jiechao Ge*, Photoluminescence Enhancement of Carbon Dots by Surfactants at Room Temperature, Chem. Eur. J. 2018, 24, 15806 – 15811.
16. Wei Ren, Lingyu Han, Mengyi Luo, Baolin Bian, Ming Guan, Hui Yang, Chao Han, Na Li, Tuo Li, Shilei Li, Yangyang Zhang, Zhenwen Zhao,* Haiyu Zhao, Multi-component identification and target cell-based screening of potential bioactive compounds in toad venom by UPLC coupled with high-resolution LTQ-Orbitrap MS and high-sensitivity Qtrap MS, Analytical and Bioanalytical Chemistry (2018) 410:4419–4435.
17. Yangyang Zhang, Shilei Li, Zhenwen Zhao*, Using nanoliposomes to construct a FRET-based ratiometric fluorescent probe for sensing intracellular pH values, Anal. Chem. 2016, 88, 12380-12385.
18. Yangyang Zhang, Jun Wang, Jian’an Liu, Juanjuan Han, Shaoxiang Xiong, Weidong Yong, Zhenwen Zhao*, Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain. Sci. Rep. 2016, 6, 25289.
19. Yangyang Zhang, Yingying Liu, Lin Li, Jinchao Wei, Shaoxiang Xiong, Zhenwen Zhao*, High resolution mass spectrometry coupled with multivariate data analysis revealing plasma lipidomic alteration in ovarian cancer in Asian women. Talanta 2016, 150, 88-96.
20. Shilei Li, Yangyang Zhang, Jian’an Liu, Juanjuan Han, Ming Guan, Hui Yang, Yu Lin, Shaoxiang Xiong, Zhenwen Zhao*, Electrospray deposition device used to precisely control the matrix cystal to improve the performance of MALDI MSI, Sci. Rep. 2016, 6, 37903.
21. Yanbo Wei, Yangyang Zhang, Yu Lin, Lin Li, Jian’an Liu, Zhenpeng Wang, Shaoxiang Xiong, Zhenwen Zhao*, A uniform DHB layer as matrix for MALDI-FTICRMS-based lipidomics. Analyst 2015, 140, 1298-1305.
21. Lin Li, Linlin Wang, Dihua Shangguan, Yanbo Wei, Juanjuan Han, Shaoxiang Xiong, Zhenwen Zhao,∗ Ultra-high-performance liquid chromatography electrosprayionization tandem mass spectrometry for accurate analysis ofglycerophospholipids and sphingolipids in drug resistance tumor cells, Journal of Chromatography A, 1381 (2015) 140–148.
22. Lin Li, Juanjuan Han, Zhenpeng Wang, Jian’an Liu, Jinchao Wei, Shaoxiang Xiong, Zhenwen Zhao,∗ Mass spectrometry methodology in lipid analysis, Int. J. Mol. Sci. 2014, 15, 10492-10507.
23. Yanbo Wei, Shumu Li, Jingxia Wang, Chunying Shu, Jian’an Liu, Shaoxiang Xiong, Jianwen Song, Junjie Zhang, Zhenwen Zhao*, Polystyrene spheres-assisted MALDI MS for quantitative analysis of plasma lysophosphatidylcholines. Anal Chem. 2013, 85: 4729-4734.
24. Hailan Liu, Xi Wu, Zizheng Dong, Zhiyong Luo, Zhenwen Zhao, Yan Xu and Jian-Ting Zhang, Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production. J Lipid Res. 2013, in press.
25. Song Li, Bin Guo, Jianwen Song, Xiaoli Deng, Yusheng Cong, Pengfei Li, Ke Zhao, Lihong Liu, Gang Xiao, Feng Xu, Yingjiang Ye, Zhenwen Zhao, Menggang Yu, Yan Xu, Jianli Sang, Junjie Zhang. Plasma choline-containing phospholipids: potential biomarkers for colorectal cancer progression. Metabolomics. 2013, 9: 202–212
26. Nicholas J. Skill, Wu Jianmin, Xu Yan, Zhenweng Zhao, Alfred J. Tector, Mary A. Maluccio, Lysophospholipid variants in hepatocellular carcinoma. J Surg Res. 2012 in press.
27. (*联合第一作者) Qingchun Cai *, Zhenwen Zhao *, Caryl Antalis *, Libo Yan, Ali Hassan Hamed, Frederick B. Stehman, Jeanne M. Schilder, Giuseppe Del Priore, Yan Xu. Elevated and secreted PLA2 activities as new potential therapeutic targets in human epithelial ovarian cancer. FASEB J, 2012, 26: 3306-20.
28. Ioanna Nikitopoulou, Nikos Oikonomou, Emmanuel Karouzakis, Ioanna Sevastou, Nefeli Nikolaidou-Katsaridou, Zhenwen Zhao, Vassilis Mersinias, Maria Armaka, Yan Xu, Masayuki Masu, Gordon B. Mills, Steffen Gay, George Kollias, and Vassilis Aidinis. Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis. J Exp Med. 2012; 209: 925-33.
29. Suthat Liangpunsakul, Yasmeen Rahmini, Ruth A. Ross, Zhenwen Zhao, Yan Xu, and David W. Crabb. Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice. Am J Physiol Gastrointest Liver Physiol. 2012; 302: G515-23.
30. Manuela Funke, Zhenwen Zhao, Yan Xu, Jerold Chun, and Andrew M. Tager. The Lysophosphatidic Acid Receptor LPA1 Promotes Epithelial Cell Apoptosis after Lung Injury. Am J Respir Cell Mol Biol. 2012; 46: 355-64.
31. (*联合第一作者) Hui Li*, Zhenwen Zhao*, Caryl Antalis*, Zhanzhong Zhao, Robert Emerson, Gang Wei, Sheng Zhang, Zhong-Yin Zhang, Yan Xu. Combination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer development. Am J Pathol. 2011; 179: 452-61.
32. Jussi Pihlajamäki, Carles Lerin, Paula Itkonen, Tanner Boes, Thomas Floss, Joshua Schroeder, Farrell Dearie, Sarah Crunkhorn, Furkan Burak, Josep C. Jimenez-Chillaron, Tiina Kuulasmaa, Pekka Miettinen, Peter J. Park, Imad Nasser, Zhenwen Zhao, Zhaiyi Zhang, Yan Xu, Wolfgang Wurst, Hongmei Ren, Andrew J. Morris, Stefan Stamm, Allison B. Goldfine, Markku Laakso, Mary Elizabeth Patti., Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metab. 2011; 14: 208-18.
33. Zhenwen Zhao, Menggang Yu, Yan Xu, David Crabb, Suthat Liangpunsakul, Ethanol-induced alterations in fatty acid-related lipids in serum and tissues in mice. Alcoholism Clinical and Experimental Research, 2011, 35: 229-234.
34. Zhenwen Zhao, Yan Xu, An extremely simple method for extraction of lysophospholipids and phospholipids from blood samples. J Lipid Res, 2010, 51: 652-659. PMID: 19783525.
35. Hui Li, Zhenwen Zhao, Gang Wei, Libo Yan, Dongmei Wang, Hong Zhang, George Earl Sandusky, John Turk and Yan Xu, Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development. FASEB J. 2010; 24(10):4103-16.
36. Jian-Min Wu, Yan Xu, Nicholas J Skill, Hongmiao Sheng, Zhenwen Zhao, Menggang Yu, Romil Saxena, and Mary A Maluccio. Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma. Mol Cancer. 2010; 9:71.
37. Stella Fotopoulou, Nikos Oikonomou, Elena Grigorieva, Ioanna Nikitopoulou, Triantafillos Paparountas, Artemis Thanassopoulou, Zhenwen Zhao, Yan Xu, Dimitris L. Kontoyiannis, Eumorphia Remboutsika, Vassilis Aidinis. ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol. 2010; 339(2):451-64.
38. Suthat Liangpunsakul, Margaret S. Sozio, Eric Shin, Zhenwen Zhao, Yan Xu, Ruth A. Ross, Yan Zeng, and David W. Crabb. Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels. Am J Physiol Gastrointest Liver Physiol. 2010; 298(6):G1004-12.
39. Sung-Jo Kim, Zhongjian Zhang, Arjun Saha, Chinmoy Sarkar, Zhenwen Zhao, Yan Xu, Anil B. Mukherjee. Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1. Neurosci Lett. 2010; 479: 292-6.
40. Zhenwen Zhao, Yan Xu, Accurate measurement of lysophosphatidic acid by ESI-MS/MS in plasma samples requires pre-separation of lysophosphatidylcholine. J Chrom B, 2009, 877: 3739-3742.
41. Hui Li, Dongmei Wang, Hong Zhang, Kashif Kirmani, Zhenwen Zhao, Rosemary Steimetz, and Yan Xu, Lysophosphatidic acid stimulates cell migration, invasion, and colony formation as well as tumorigenesis/metastasis of mouse ovarian cancer in immunocompetent mice. Mol. Cancer Ther. 2009, 8: 1692-1701.
42. Hui Li , Dongmei Wang , Lisam Shanjukumar Singh , Michael Berk , Haiyan Tan , Zhenwen Zhao, Rosemary Steinmetz , Kashif Kirmani , Gang Wei, Yan Xu, Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G protein-Coupled Receptor 1. Plos One, 2009; 4: e5705.
43. Dongmei Wang, Zhenwen Zhao, Andrea Caperell-Grant, Gong Yang, Samuel C. Mok, Jinsong Liu, Robert M. Bigsby and Yan Xu, S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells. Mol. Cancer Ther. 2008; 7:1993-2002.
44. Andrew M Tager, Peter LaCamera, Barry S Shea, Gabriele S Campanella, Moisés Selman, Zhenwen Zhao, Vasiliy Polosukhin, John Wain, Banu A Karimi-Shah, Nancy D Kim, William K Hart, Annie Pardo, Timothy S Blackwell, Yan Xu, Jerold Chun and Andrew D Luster, The Lysophosphatidic Acid Receptor LPA1 Links Pulmonary Fibrosis to Lung Injury by Mediating fibroblast Recruitment and Vascular Leak. Nature Medicine 2008, 14, 45-54.
45. Zhenwen Zhao, Yijin Xiao, Paul Elson, Haiyan Tan, Sarah J. Plummer, Michael Berk, Phyu Phyu Aung, Ian C. Lavery, Jean Paul Achkar, Graham Casey and Yan Xu, Plasma lysophosphatidylcholine levels: potential biomarkers for colorectal cancer. J Clin Oncology 2007, 25: 2696-2701.
46. 赵镇文,熊蕾,王振鹏,辛斌,胡伟华,熊少祥,壳聚糖的基质辅助激光解吸电离飞行时间质谱分析,分析化学2007; 35: 1025-1028.
47. Lisam Shanjukumar Singh, Michael Berk, Rhonda Oates, Zhenwen Zhao, Haiyan Tan, Ying Jiang, Aimin Zhou, Kashif Kirmani, Rosemary Steinmetz, Daniel Lindner, Yan Xu, Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. J. National Cancer Institute. 2007, 99: 1313-1327.
48. Shu Zhang, Zhenwen Zhao, Lei Xiong, Bin Xin, Weihua Hu, Shaoxiang Xiong, A novel sample preparation method of matrix-assisted laser desorption/ionization time of flight mass spectrometry for polystyrene. Chin. Chem. Letters 2007; 18: 718-721.
49. 王振鹏，赵镇文，辛 斌，胡伟华，熊少祥, 三苯胺偶氮化合物的MALDI—TOF质谱研究, 质谱学报,2007; 28(1): 27-31.
50. 刘健安,赵镇文,辛斌,胡伟华,熊少祥, 有机硼化合物的质谱分析,分析化学,2007; 35(8): 1203-1206.
51. Suying Dong, Zhenwen Zhao and Huimin Ma, Characterization of Local Polarity and Hydrophobic Binding Sites of â-Lactoglobulin by Using N-Terminal Specific Fluorescence Labeling. J. Proteome Research, 2006; 5: 27-31.
52. Xiaoxian Zhao, Dongmei Wang, Zhenwen Zhao, Yingyi Xiao, Saubhik Sengupta, Yijin Xiao, Renliang Zhang, Kirsten Lauber, Sebastian Wesselborg, Li Feng, Tyler M. Rose, Yue Shen, Junjie Zhang, Glenn Prestwich, and Yan Xu, Caspase-3-dependent Activation of Calcium-independent Phospholipase A2 Enhances Cell Migration in Non-apoptotic Ovarian Cancer Cells. J. Biol. Chem 2006; 281: 29357-29368.
53. Juan Ren, Yi-jin Xiao, Lisam Shanjukumar Singh, Xiaoxian Zhao, Zhenwen Zhao, Li Feng, Tyler M. Rose, Glenn D. Prestwich, and Yan Xu, Lysophosphatidic Acid Is Constitutively Produced by Human Peritoneal Mesothelial Cells and Enhances Adhesion, Migration, and Invasion of Ovarian Cancer Cells. Cancer Res 2006; 66: 3006-3014.
54. 熊少祥, 赵镇文, 蒲丹,辛斌, 王光辉, 液相基质辅助激光解吸电离-傅里叶变换离子回旋共振质谱研究, 分析化学, 2004; 32(1): 14-18.
55. Zhenwen Zhao, Shaoxiang Xiong, Xiangwen Liu, Bin Xin and Guanghui Wang. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Studies of Low Molecular Weight Dendrimers. Eur J Mass Spectrom. 2003, 9: 203-211.
56. Shaoxiang Xiong, Zhenwen Zhao, Bin Xin and Guanghui Wang. Characterization of Macrocyclic Polysaccharides Using Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry. Rapid Commu. Mass Spectrom. 2003; 17: 1079-1083.
57. Shaoxiang Xiong, Qinxue Ding, Zhenwen Zhao, Wenzhang Chen, Guanghui Wang and Shaojun Liu. A New Method to Improve Sensitivity and Resolution in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Proteomics 2003; 3: 265-272.
58. hikun Wu, Qingqi Chen, Shaoxiang Xiong, Bin Xin, Zhenwen Zhao, Lijin Jiang, and Jin Shi Ma. Double-Stranded Helicates, Triangles, and Squares Formed by the Self-Assembly of Pyrrol-2- ylmethyleneamines and ZnII Ions. Angew. Chem. Int. Ed. 2003; 42: 3271-3274.