赵耀助理研究员----中国科学院活体分析化学重点实验室

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赵耀助理研究员

出生年月：1983年6月

电话：010-62529069

Email: yaozhao@iccas.ac.cn

学习和科研经历

2001.9~2005.6 南京大学化学化工学院毕业，获学士学位

2005.9~2008.6 南京大学化学化工学院毕业，获硕士学位

2008.9~2012.6 英国华威大学化学系毕业，获博士学位

代表文章

1. Zhao, Y; Woods, J. A. Farrer, N. J.; Robinson, K. S.; Pracharova, J.; Kasparkova, J.; Novakova, O.; Li, H.; Salassa, L.; Pizarro, A. M.; Clarkson, G. J.; Song, L,; Brabec, V.; Sadler, P. J.^*; Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts, Chem. Eur. J, published online, DOI: 10.1002/chem.201300374.

2. Zhao, Y.; Roberts, G. M.; Greenough, S. E.; Farrer, N. J.; Paterson, M. J.; Powell, W. H.; Stavros, V. G.; Sadler, P. J.^*, Two-photon-activated ligand exchange in platinum(II) complexes. Angew. Chem. Int. Ed. 2012, 51 (45), 11263-11266.

3. Tai, H.-C.^†; Zhao, Y.^†; (^†, equal contribution) Farrer, N. J.; Anastasi, A. E.; Clarkson, G.; Sadler, P. J.^*; Deeth, R. J.^*, A computational approach to tuning the photochemistry of platinum(IV) anticancer agents, Chem. Eur. J, 2012, 18 (34), 10630-10642.

4. Li, H.; Wells, S. A.; Jimenez-Roldan, J. E.; Römer, R. A.; Zhao, Y.; Sadler, P. J.; O'Connor, P. B.^*, Protein flexibility is key to cisplatin crosslinking in calmodulin. Protein Sci. 2012, 21 (9), 1269-1279.

5. Li, H.; Lin, T.-Y.; Van Orden, S. L.; Zhao, Y.; Barrow, M. P.; Pizarro, A. M.; Qi, Y.; Sadler, P. J.; O’Connor, P. B.^*, Use of Top-Down and Bottom-Up Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Mapping Calmodulin Sites Modified by Platinum Anticancer Drugs. Anal. Chem. 2011, 83 (24), 9507-9515.

6. Li, H.; Zhao, Y.; Phillips, H. I. A.; Qi, Y.; Lin, T.-Y.; Sadler, P. J.; O’Connor, P. B.^*, Mass Spectrometry Evidence for Cisplatin As a Protein Cross-Linking Reagent. Anal. Chem. 2011, 83 (13), 5369-5376.

7. Farrer, N. J.; Woods, J. A.; Salassa, L.; Zhao, Y.; Robinson, K. S.; Clarkson, G.; Mackay, F. S.; Sadler, P. J.^*, A Potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light. Angew. Chem. Int. Ed. 2010, 49 (47), 8905-8908.

8. Kan, X.; Geng, Z.; Zhao, Y.; Wang, Z.^*; Zhu, J.-J.^*, Magnetic molecularly imprinted polymer for aspirin recognition and controlled release. Nanotechnology 2009, 20 (16), 165601.

9. Kan, X. W.; Zhao, Y.; Geng, Z. R.; Zhu, J. J.^*; Wang, Z. L.^*, Composites of multiwalled carbon nanotubes and molecularly imprinted polymers for dopamine recognition. J. Phys. Chem. C 2008, 112 (13), 4849-4854.