学习经历
2007年1月 中国科学院理化技术研究所硕博连读 理学博士
1992年6月 湖南师范大学化学系毕业,获理学学士学位
工作经历
2009-至今 中国科学院化学研究所活体分析化学院重点实验室汪福意课题组助理研究员、副研究员
2007-2009 中国科学院化学研究所活体分析化学院重点实验室汪福意课题组博士后
1992-1999 长沙航空职业技术学院助教,讲师
学术任职 中国化学会会员
代表论文
1. Qun Luo, Jianhua Cao, Daihua Tang*, Dayong Wu,Yong Huang, Junfeng Xiang, Fuyi Wang*, Xinhou Liu, GangWu* Lipophilic thioguanosine: an anion receptor for cesium fluoride, Journal of Fluorine Chemistry, (DOI: http://dx.doi.org/doi:10.1016/j.jfluchem.2013.02.020)
2. S. Lü, W. Zheng, L. Ji, Q. Luo*, X. Hao, X. Li, F.-Y. Wang*, Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors, Eur. J. Med. Chem. 2013, 61, 84-94.
3. Wenbing Hu, Jianan Liu, Qun Luo*,Yumiao Han, Kui Wu, Shuang Lv, Shaoxiang Xiong, and Fuyi Wang*,. Elucidation of the Binding Sites of Sodium Dodecyl Sulfate to -Lactoglobulin Using Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Docking Simulation, Rapid Commun. Mass Spectrom., 2011, 25, 1429-1436.
4. Qun Luo,Dayong Wu, Shixiong Liu, Daihua Tang, Yong Huang, Xinhou Liu, Fuyi Wang, Ruiyao Wang, and Gang Wu. The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects. Organic & Biomolecular Chemistry, 2011, 9, 1030-1033
5. Qun Luo, Daihua Tang, Gang Wu. Ribose-protected Thioguanosine-based 1H. NMR Spectroscopic Probe for the Detection of Cesium from Solid Cesium-containing Sources in Acetonitrile. Inorganic Chemistry Communications, 2008, 11, 1359–1362.
6. Qun Luo, Daihua Tang, Xiaodong Li, Qi Wang, Zhipeng Wang, Zhen Zhen, and Xinhou Liu. Preparation of Polysilsesquioxane (CH3SiO1.5)8 Crystals from Swollen PHEMA. Chemistry Letters, 2006, 35(3), 278-279.
7. Qun Luo, Daihua Tang, Zhen Zhen, and Xinhou Liu. 2’-Deoxy-3’,5’-di-O-acetyl-uridine Acta Crystallographica Section E, 2007.63 (1) .o4-o6.
8. K. Wu, W. Hu, Q. Luo, X. Li, S. Xiong, P. Sadler, F.-Y. Wang*, Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing vs top-down, J. Am. Soc. Mass. Spectrom., 2013, 24, 410-420.
9. L. Ji, J.-H. Wu, Q. Luo, X. Li, W. Zheng, G. Zhai, F.-Y. Wang*, S. Lü, Y.-Q. Feng*, J. Liu, S. Xiong, Quantitative Mass Spectrometry Combined with Separation and Enrichment of Phosphopeptides by Titania Coated Magnetic Mesoporous Silica Microspheres for Screening of Protein Kinase Inhibitors, Anal. Chem. 2012, 84, 2284-2291.
10. K. Wu, Q. Luo, W. Hu, X. Li, F.-Y. Wang*, S. Xiong, P. J. Sadler*, Mechanism of Interstrand Migration of Organoruthenium Anticancer Complexes within a DNA Duplex, Matallomics, 2012, 4, 136-148.
11. Y. M. Han, Q. Luo, X. Hao, X. C. Li, F. Y. Wang,* W. B. Hu, K. Wu, S. Lü, P. J. Sadler*, reactions of an organoruthenium anticancer complex with 2-mercaptobenzanilide - a model for the active-site cysteine of protein tyrosine phosphatase 1B, Dalton Trans. 2011, 40, 11519-11529
12. W.B. Hu, Q. Luo, K. Wu, X.C. Li, F.Y. Wang,* Y. Chen, X.Y. Ma, J.P. Wang, J.A. Liu,a S.X. Xiong, P.J.. Sadler*, the anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin, Chem. Commun. 2011, 47, 6006–6008.
13. S. Lv, Q. Luo, X. C. Li, K. Wu, J. A. Liu, S. X. Xiong, Y.Q. Feng, F.Y. Wang*, Inhibitor Screening of Protein Kinases Using MALDI-TOF MS Combined with Separation and Enrichment of Phosphopeptides by TiO2 Nanoparticle Deposited Capillary Column, Analyst, 2010, 135, 2858-2863.
14. W. B. Hu, Q. Luo, X. Y. Ma, K. Wu, J. A. Liu, Y. Chen, S. X. Xiong, J. P. Wang, P. J. Sadler, F. Y. Wang,* arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes, Chem. Eru. J. 2009, 15, 6586-6594
15. Daihua Tang, Dayong Wu, Qun Luo, Wenbing Hu, Fuyi Wang, Shixiong Liu, Xinhou Liu, and Qinghua Fan. Single-Molecule Behavior of Dendritic Poly(ethylene glycol) Structures towards Lithium Ions. Chem. Eur. J., 2009, 15, 10352 – 10355
承担的科研项目
1. 2011.1-2011.12,国家基金委委主任基金项目:氢交换质谱研究蛋白质与DNA药物复合物之间的相互作用(项目批准号:21055002),主持,总经费10万元。(已结题)
2. 2012.7-2014.6,2012 年化学所培育项目:“生物活性荧光探针的构建及肿瘤活细胞成像分析研究”,(批准号:CMS-PY-201240),主持,总经费10万元。
3. 2013.1-2016.12,国家基金委面上项目:微纳米DNA 探针捕获蛋白质-质谱分析联用研究肿瘤细胞对金属抗肿瘤药物的应答机制(批准号:21275148),主持,总经费80万元。
4. 2012.1-2016.12,国家自然科学基金委国家重大科研仪器研制项目:高分辨多功能化学成像系统,骨干成员,超分辨光学成像-二次离子质谱成像联用系统研制子课题负责人,子课题经费 900万元 (项目总经费 7000万元)
5. 2012.1-2016.12,国家自然科学基金重点项目:调控蛋白与药物损伤DNA相互作用研究的分析新方法(21135006),骨干成员,总经费300万元
6. 2010.1-2012.12, 国家自然科学基金委面上项目:LC-MS研究金属抗肿瘤药物与血清蛋白的相互作用(20975103),骨干成员,总经费 35万元
7. 2008.1-2010.12,国家自然科学基金重大研究计划项目:基于信号转导过程的组合分子抗癌药物的设计和作用机理研究(90713020),骨干成员,总经费50万元(已结题)
8. 2007.1-2012.6,中国科学院“百人计划”项目:多功能化学小分子探针的构建及其在信号转导研究和药物设计中的应用,骨干成员,总经费,300万元(已结题)
9. 2007.3-2007.12,国家自然科学基金科学部主任基金项目:液质联用和多维核磁波谱研究组合分子抗癌药物与生物靶分子的相互作用(20745002),骨干成员,总经费8万元(已结题)
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