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Dr Qun Luo
时间:2013-05-09 浏览:
  
 

Dr Qun Luo, Associate Professor

Date of Birth: Apr, 1970

Tel: 010-62529069

Mobil: 13520735629

Email: qunluo@iccas.ac.cn 

Education and Work Experience

1992.6:               BSc., Hunan Normal University

2007.3:               Ph.D., The Technical Institute of Physics and Chemistry , CAS

1992 – 1999       Lecturer, Changsha Aeronautical Vocational and Technical College

2007 – 2009:      Postdoctor, Institute of Chemistry, CAS

2009 – now     Associate Professor, Institute of Chemistry, CAS

Professional Qualifications

l  Member of the Chinese Society of Chemistry.

Selective Publications

1.   Qun Luo, Jianhua Cao, Daihua Tang*, Dayong Wu,Yong Huang, Junfeng Xiang, Fuyi Wang*, Xinhou Liu, GangWu* Lipophilic thioguanosine: an anion receptor for cesium fluoride, Journal of Fluorine Chemistry, (DOI: http://dx.doi.org/doi:10.1016/j.jfluchem.2013.02.020)

2.   S. Lü, W. Zheng, L. Ji, Q. Luo*, X. Hao, X. Li, F.-Y. Wang*, Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors, Eur. J. Med. Chem. 2013, 61, 84-94.

3.   Wenbing Hu, Jianan Liu, Qun Luo*Yumiao Han, Kui Wu, Shuang Lv, Shaoxiang Xiong, and Fuyi Wang*,. Elucidation of the Binding Sites of Sodium Dodecyl Sulfate to -Lactoglobulin Using Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Docking Simulation, Rapid Commun. Mass Spectrom., 2011, 25, 1429-1436.

4.   Qun LuoDayong Wu, Shixiong Liu, Daihua Tang, Yong Huang, Xinhou Liu, Fuyi Wang, Ruiyao Wang, and Gang Wu. The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects. Organic & Biomolecular Chemistry, 2011, 9, 1030-1033

5.   Qun Luo, Daihua Tang, Gang Wu. Ribose-protected Thioguanosine-based 1H. NMR Spectroscopic Probe for the Detection of Cesium from Solid Cesium-containing Sources in Acetonitrile. Inorganic Chemistry Communications, 2008, 11, 1359–1362.

6.   Qun Luo, Daihua Tang, Xiaodong Li, Qi Wang, Zhipeng Wang, Zhen Zhen, and Xinhou Liu. Preparation of Polysilsesquioxane (CH3SiO1.5)8 Crystals from Swollen PHEMA. Chemistry Letters, 2006, 35(3), 278-279.

7.   Qun Luo, Daihua Tang, Zhen Zhen, and Xinhou Liu. 2’-Deoxy-3’,5’-di-O-acetyl-uridine Acta Crystallographica Section E, 2007.63 (1) .o4o6.

8.   K. Wu, W. Hu, Q. Luo, X. Li, S. Xiong, P. Sadler, F.-Y. Wang*, Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing vs top-down, J. Am. Soc. Mass. Spectrom., 2013, 24, 410-420.

9.   L. Ji, J.-H. Wu, Q. Luo, X. Li, W. Zheng, G. Zhai, F.-Y. Wang*, S. Lü, Y.-Q. Feng*, J. Liu, S. Xiong, Quantitative Mass Spectrometry Combined with Separation and Enrichment of Phosphopeptides by Titania Coated Magnetic Mesoporous Silica Microspheres for Screening of Protein Kinase Inhibitors, Anal. Chem. 2012, 84, 2284-2291.

10. K. Wu, Q. Luo, W. Hu, X. Li, F.-Y. Wang*, S. Xiong, P. J. Sadler*, Mechanism of Interstrand Migration of Organoruthenium Anticancer Complexes within a DNA Duplex, Matallomics, 2012, 4, 136-148.

11. Y. M. Han, Q. Luo, X. Hao, X. C. Li, F. Y. Wang,* W. B. Hu, K. Wu, S. Lü, P. J. Sadler*, reactions of an organoruthenium anticancer complex with 2-mercaptobenzanilide - a model for the active-site cysteine of protein tyrosine phosphatase 1B, Dalton Trans. 2011, 40, 11519-11529

12. W.B. Hu, Q. Luo, K. Wu, X.C. Li, F.Y. Wang,* Y. Chen, X.Y. Ma, J.P. Wang, J.A. Liu,a S.X. Xiong, P.J.. Sadler*, the anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin, Chem. Commun. 2011, 47, 6006–6008.

13. S. Lv, Q. Luo, X. C. Li, K. Wu, J. A. Liu, S. X. Xiong, Y.Q. Feng, F.Y. Wang*, Inhibitor Screening of Protein Kinases Using MALDI-TOF MS Combined with Separation and Enrichment of Phosphopeptides by TiO2 Nanoparticle Deposited Capillary Column, Analyst, 2010, 135, 2858-2863.

14. W. B. Hu, Q. Luo, X. Y. Ma, K. Wu, J. A. Liu, Y. Chen, S. X. Xiong, J. P. Wang, P. J. Sadler, F. Y. Wang,* arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes, Chem. Eru. J. 2009, 15, 6586-6594

15. Daihua Tang, Dayong Wu, Qun Luo, Wenbing Hu, Fuyi Wang, Shixiong Liu, Xinhou Liu, and Qinghua Fan. Single-Molecule Behavior of Dendritic Poly(ethylene glycol) Structures towards Lithium Ions. Chem. Eur. J., 2009, 15, 10352 – 10355

 

Current Research Projects

1.       2013.1- 2016.12NSFC General Project: Investigations on mechanism of cellular responses to metal-based antitumor drugs by mass spectrometry combined with capturing of proteins by micro-/nano-DNA probes (21275148)0.80 million CNY.

2.       2012.7-2014.62012 Institute of Chemistry Cultivated Project: Construction of   bioactivity fluorescent probes and Analysis of imaging of living cancer cells. (CMS-PY-201240), 0.10million CNY

3.       2012.1-2016.12, NSFC National Major Research Project on Scientific Instruments: High resolution and multi-functional chemical imaging system, 8.7 million CNY

4.       2012.1-2016.12, NSFC Key ProjectMethodology for investigations on interactions between regulating protein and DNA damaged by drug (21135006), 3 million CNY

5.       2010.1-2012.12, NSFC General Project: Investigation of interactions between organometallic ruthenium anticancer complexes and serum proteins (20975103), 0.35 million CNY

 
 
 
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