Dr Yao Zhao----中国科学院活体分析化学重点实验室

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Dr Yao Zhao

Date of Birth: Jun, 1983

Tel: 010-62529069

Email: yaozhao@iccas.ac.cn

Study and research experience

2001.9~2005.6 B.S. Chemistry, Nanjing University, P. R. China

2005.9~2008.6 M.S. Chemistry, Nanjing University, P. R. China

2008.9~2012.6 PhD Chemistry, University of Warwick, UK

Selective Publiations

1. Zhao, Y; Woods, J. A. Farrer, N. J.; Robinson, K. S.; Pracharova, J.; Kasparkova, J.; Novakova, O.; Li, H.; Salassa, L.; Pizarro, A. M.; Clarkson, G. J.; Song, L,; Brabec, V.; Sadler, P. J.*; Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts, Chem. Eur. J, published online, DOI: 10.1002/chem.201300374.

2. Zhao, Y.; Roberts, G. M.; Greenough, S. E.; Farrer, N. J.; Paterson, M. J.; Powell, W. H.; Stavros, V. G.; Sadler, P. J.*, Two-photon-activated ligand exchange in platinum(II) complexes. Angew. Chem. Int. Ed. 2012, 51 (45), 11263-11266.\

3. Tai, H.-C.†; Zhao, Y.†; (†, equal contribution) Farrer, N. J.; Anastasi, A. E.; Clarkson, G.; Sadler, P. J.*; Deeth, R. J.*, A computational approach to tuning the photochemistry of platinum(IV) anticancer agents, Chem. Eur. J, 2012, 18 (34), 10630-10642.

4. Li, H.; Wells, S. A.; Jimenez-Roldan, J. E.; Römer, R. A.; Zhao, Y.; Sadler, P. J.; O'Connor, P. B.*, Protein flexibility is key to cisplatin crosslinking in calmodulin. Protein Sci. 2012, 21 (9), 1269-1279.

5. Li, H.; Lin, T.-Y.; Van Orden, S. L.; Zhao, Y.; Barrow, M. P.; Pizarro, A. M.; Qi, Y.; Sadler, P. J.; O’Connor, P. B.*, Use of Top-Down and Bottom-Up Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Mapping Calmodulin Sites Modified by Platinum Anticancer Drugs. Anal. Chem. 2011, 83 (24), 9507-9515.

6. Li, H.; Zhao, Y.; Phillips, H. I. A.; Qi, Y.; Lin, T.-Y.; Sadler, P. J.; O’Connor, P. B.*, Mass Spectrometry Evidence for Cisplatin As a Protein Cross-Linking Reagent. Anal. Chem. 2011, 83 (13), 5369-5376.

7. Farrer, N. J.; Woods, J. A.; Salassa, L.; Zhao, Y.; Robinson, K. S.; Clarkson, G.; Mackay, F. S.; Sadler, P. J.*, A Potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light. Angew. Chem. Int. Ed. 2010, 49 (47), 8905-8908.

8. Kan, X.; Geng, Z.; Zhao, Y.; Wang, Z.*; Zhu, J.-J.*, Magnetic molecularly imprinted polymer for aspirin recognition and controlled release. Nanotechnology 2009, 20 (16), 165601.

9. Kan, X. W.; Zhao, Y.; Geng, Z. R.; Zhu, J. J.*; Wang, Z. L.*, Composites of multiwalled carbon nanotubes and molecularly imprinted polymers for dopamine recognition. J. Phys. Chem. C 2008, 112 (13), 4849-4854.